Science Highlights

• Science Highlights: 2016-2017
   
  • Crenomytilus grayanus Lectin, CGL, Could Be Developed into a Potential Biosensor for Cancer Diagnosis
  • MshE: An Important Cyclic di-GMP Receptor and Its Involvement in Formation of a Biofilm of Vibrio cholerae
  • MoeN5: An Important Prenyltransferase Involved in Moenomycin Biosynthesis
  • How the Fidelity of DNA Repair Is Modulated in Human Beings
  • Role of Dimeric Endonuclease G in DNA Degradation
  • Molecular Averaging Is Powerful for Crystal Structures
     
• Science Highlights: 2015-2016
   
  • Insight into Bridging and Condensing DNA for Chromosome Partitioning
  • How Do Pathogenic Bacteria Disable the Host Immune System in Phagocytosis?
  • Predicament of the Cultured Shrimp Industry: An Emergent Bacterial Disease Causes Substantial Economic Losses
  • Structure of the Deadly Grouper Fish Virus is Revealed
  • Discovery of a Bacterial Antigenic Loop and a New Detox Mechanism for Typhoid Treatment
  • Klebsiella pneumoniae Antimicrobial Drug Resistance: Transcriptional Regulation by Response Regulator PmrA
     
• Science Highlights: 2014-2015
   
  • Pumping Bacterial Diterpene Synthases: A Tale of Two Conserved Domains
  • Developing Novel Antibiotics to Kill Vancomycin-Resistant Enterococcus
  • New Directions for Therapeutic Treatment of Colorectal Cancer
  • Resolving the Phase Ambiguity of Single-Wavelength Anomalous Dispersion
  • Crowning Proteins: Modulating the Protein Properties using Crown Ethers
     
• Science Highlights: 2013-2014
   
  • Protein-Protein Interaction
  • Drug Discovery with Protein X-ray Crystallography
  • A Lon Story
     
• Science Highlights: 2012-2013
   
  • Pumping Protons against Gradients into a Plant Vacuole
  • Stop Building a Cell Wall
  • The First Step in a Synthesis of Antibiotic Moenomycin
  • Starve Cancer Cells by Cutting the Food Supply
  • To Cut or Not to Cut?
     
• Science Highlights: 2011-2012
   
  • Direct Observation of an Deadly DNA Breakage Induced by Anticancer Drug Etoposide and Type II Topoisomerase
  • Structural Basis for Differential RNA Trimming by RNase T in Stable RNA 3-end Maturation
  • Study of Hexose Oxidase Yields New Antibiotics
  • Structural Basis for the Methylation of the Small Ribosomal Subunit by NpmA from a Clinical Isolate
     
• Science Highlights: 2010-2011
   
  • Diversity in P-loop Structure of A-ATP Synthase
  • Actin Filament Capping Regulators
  • Structural Study of TcaR with Antibiotics
  • Dynamics of Dengue Virus NS3 Protease and Helicase Domain
  • Wrap Double Standed DNA with Spiral-shape -Pinwheel
     
• Science Highlights: 2009-2010
   
  • Crystal Structure of the Membrane-bound Bifunctional Transglycosylase PBP1b from Escherichia Coli
  • Structural Studies of TDP-43- a New Player in Neurodegenerative Diseases
  • The Crystal Structure of a Replicative Hexameric Helicase DnaC and Its Complex with Single-stranded DNA
  • Divergences of Rib7 and RibG Reductases Involved in Riboflavin Biosynthesis
  • Key Insights into the Activation of Gelsolin Superfamily of Proteins
     
• Science Highlights: 2008-2009
   
  • A Cholesterol Biosynthesis Inhibitor Blocks Staphylococcus Aureus Virulence
  • Human Tudor-SN in MicroRNA Binding and Degradation
     
• Science Highlights: 2007-2008
   
  • Dual Binding Sites for Translocation Catalysis by E. Coli Glutathionylspermidine Synthetase
  • Complex Structures of Bacillus subtilis RIBG Mechanisms of Deamination and Reduction in Riboflavin Biosynthesis
  • Structural Research in Helicobacter pylori Targets for Discovery of Anti-bacterial Agents and in Biocatalysts of Chiral Reaction
  • The Crystal Structure of XC1258 from Xanthomonas Campestris
     
• Science Highlights: 2006-2007
   
  • PriB-ssDNA Structure and Suggestion of A Novel Single-stranded DNA Binding Model
  • Crystal Structure of the Human Prostacyclin Synthase
     
• Science Highlights: 2005-2006
   
  • Stereoselective Esterase from Pseudomonas putida for D-βAcetylthioisobutyric Acid Synthesis
  • Crystal Structure of A Bifunctional Deaminase and Reductase Involved in Riboflavin Biosynthesis
  • Crystal Structures of Human Glutaminyl Cyclase, an Enzyme Possibly Involved in Alzheimer’s Disease and Osteoporosis
  • Structure-Based Drug Design of a Novel Family of PPARg  Partial Agonists: Virtual Screening, X-ray Crystallography and In Vitro/In Vivo Biological Activities
     
• Science Highlights: 2004-2005
   
  • Structure of the Topoisomerase IV C-terminal Domain from Bacillus stearothermophilus
  • Citrate-dependent Heparan Sulfate-mediated Cell Surface Retention of Cobra Cardiotoxin A3
  • Crystal Structure of Escherichia coli primosomal protein PriB
  • Crystal Structures of Fungal Volvatoxin A2
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• Science Highlights: 2003-2004
   
  • Visualization of Cell-defending Nonspecific Nucleasesin DNA Recognition and Cleavage
  • The Functional Role of Binuclear Metal Center in D-aminoacylase One-Mental Activation and Second-Metalattenuation
  • Structure and Function of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima
  • Crystal Structure of Nucleoside Diphosphate Kinase from Rice